Application
Fluorinated piperidines are of interest in drugs, agrochemicals and materials science. A straightforward process developed by Glorius and coworkers allows the preparation of these motifs in a highly diastereoselective manner. The all-cis-3,5-difluoropiperidine can be directly employed in synthetic applications after TFA-deprotection.
This product has met the following criteria to qualify for the following awards: